hrp0097p1-501 | GH and IGFs | ESPE2023

The Predictive Value of using IGF1/Growth Hormone Peak Ratio on growth parameters in Children with Growth Hormone Deficiency (GHD) before and after GH treatment.

Soliman Ashraf , Alyafei Fawzia , Alaaraj Nada , Hamed Noor , Ahmed Shayma , Elsiddig Sohair , Eldarsy Nagwa

Introduction: GH stimulates the production of IGF1; however, their metabolic effects are different. GH has lipolytic and anti-insulin actions while IGF1 has insulin-like actions.Objectives: To investigate the value of using the IGF1/GH peak ratio in relation to the anthropometric data of children with growth hormone deficiency (GHD) before and after a year of GH therapy.Patients and Methods...

hrp0097p1-117 | Growth and Syndromes | ESPE2023

Evaluating the Beneficial Role of Nutritional Intervention (NI) Trials in Improving Growth in Children with Beta Thalassemia Major (BTM)

Soliman Ashraf , Ahmed Shyama , Alaaraj Nada , Alyafei Fawzia , Hamed Noor , Itani Maya

Introduction: Patients with thalassemia have a high prevalence of malnutrition and low body mass index (BMI), and nutritional intervention studies are scarce.Aim: We performed an electronic search in PubMed, Google Scholar, and Web of Sciences to review nutritional intervention studies and their possible beneficial effect on children and adults with BTM.Results: 17 controlled and/o...

hrp0097p1-308 | Growth and Syndromes | ESPE2023

Birth Size and Postnatal Growth in Infants with Solitary Kidney: Does the disease affect Growth?

Soliman Ashraf , Elbaba Mustafa , Mehta Shital , Hamed Noor , Alaaraj Nada , Alyafei Fawzia , Ahmed Shayma

Introduction: Infants with solitary functioning kidney (SFK) may be prone to develop growth problems, which are not well represented in the literature.Objectives: The aim of this study was to evaluate birth size and postnatal growth in infants with SFK.Patients and Methods: We measured the weight, Weight SDS (WAZ), length SDS (LAZ), and weight for length SDS (WLZ) at birth and ever...

hrp0097p1-508 | Growth and Syndromes | ESPE2023

Placental measurements in relation to gestational age (GA) and fetal growth Characteristics (SGA, AGA and LGA) in a large Cohort in Qatar(n= 80722).

Alyafei Fawzia , Soliman Ashraf , Olukade Tawa , Alqubaisi Mai , Alaaraj Nada , Ali Hamdy

Background: Epidemiological studies have shown associations between placental weight (PW) and perinatal and postnatal linear growth and weight gain.Objectives: To report trimmed placental weight (PWT) and evaluate their association with birth weight (BWT), and gestational age (GA) in a large cohort of mother/ baby pairs in Qatar. (n= 80722).Methods: Retrospective data anal...

hrp0097p1-525 | Growth and Syndromes | ESPE2023

Human milk insulin-like growth factor-1 (HMIGF1) and its effects on Infantile and Childhood Growth

Soliman Ashraf , Alyafei Fawzia , Alaaraj Nada , Hamed Noor , Ahmed Shayma , Soliman Nada , Shaat Mona , Adel Ashraf

Introduction: Accumulating evidence indicates various but significant effects of human breast milk IGF1 (HMIGF1) on infantile linear growth and weight gain.Objectives and Methods: We performed electronic literature systematic review using PubMed, Google Scholar, and Web of Sciences with the aim to provide an update on various effects of HMIGF1 on infantile and childhood growth. We reviewed 12 studies (n= 941 inf...

hrp0097p2-126 | Diabetes and Insulin | ESPE2023

Relationship Between Time in Range (TIR), Time Below Range (TBR), Time Above Range (TAR), Glycemic Variability (GV), and HbA1c as predictor of glycemic control in children and adolescents with Type 1 Diabetes Mellitus.

Ahmed Shayma , Soliman Ashraf , Hussain Mona , Alyafei Fawzia , Alaaraj Nada , Hamed Noor

Introduction: Glycated hemoglobin (HbA1c) is a rough indicator of glycemic control and not useful to evaluate aspects related to acute or daily glycemic changes in diabetic patients. With the emphasis on intensive management of type 1 diabetes (T1DM), data from studies support using Continuous Glucose Monitoring (CGM) to improve glycemic control and reduce glucose variability, which is related to an increase in macro and microvascular complications.<p clas...

hrp0097p2-31 | Fat, Metabolism and Obesity | ESPE2023

Can Gender differently affect Growth and Metabolic Syndrome (MetS) Criteria in children with Classic Congenital Adrenal Hyperplasia (CAH)?

El Sayed Shayma , Soliman Ashraf , Hamed Noor , Alyafei Fawzia , Alaaraj Nada , Ahmed Shayma

we compared gender effect on growth and metabolic control with CAH. Morbidities associated with CAH, including risks of obesity, hypertension, dysglycemia, and dyslipidemia were investigated.Methods: Data from 30 children with CAH were analyzed retrospectively. They received hydrocortisone (n= 11) or prednisolone (n= 19) and fludrocortisone (0.1: 0.15 mg OD) since early infancy. The mean hydrocortisone dose = 22.5 +/- 7...

hrp0097p2-67 | Fat, Metabolism and Obesity | ESPE2023

The outcome of management for childhood obesity during COVID19 pandemic (2019-2021) in Qatar

Hamed Noor , Shaat Mona , Soliman Ashraf , Alyafei Fawzia , Alaaraj Nada , Ahmed Shayma

Introduction: Obesity is serious health concern that affect the children during pandemic due to school closing and shifting to online teaching with suspension of almost all physical activity. In addition, many overweight and obese children had irregular meal timing, frequent snacking, and increased screen time at home.Objectives: To study the effect of COVID 19 on weight gain during the lock- down and shifting to online ...

hrp0097p2-132 | Fat, Metabolism and Obesity | ESPE2023

Body composition changes during interventions to treat obesity in children

Soliman Ashraf , Hamed Noor , Shaat Mona , Alaaraj Nada , Alyafei Fawzia , Alyousef Doaa

Introduction: Nutrition, bodily activity, and behavior-modifying practices are recognized interventions in managing obesity. Our aim was to review available information on the short-term effects of intervention (3-4 months) on body composition of overweight and obese children and adolescents.Methods: We reviewed the anthropometric data (Weight, height (HtSD), and BMI of 16 obese children aged 12 +/- 2.2 years. Body compo...

hrp0097p2-47 | GH and IGFs | ESPE2023

The Interaction between Growth Hormone (GH) -Insulin-like Growth factor 1 (IGF1) axis and Immune Systems in Infants and Children During undernutrition: Newly Discovered Pathological mechanisms.

Soliman Ashraf , Alaaraj Nada , Rogol Alan , Alyafei Fawzia , Hamed Noor , Ahmed Shayma , Soliman Nada

Accumulating evidence indicates various interactions between the GH-IGF1 axis and the immune system in infants and children during undernutrition.Objectives and Methods: We performed electronic literature systematic review using PubMed, Google Scholar, and Web of Sciences with the aim to provide an update on the link between the GH-IGF1 axis and the immune system in infants and children during malnutrition. We reviewed 22 studies (2007-2...